【英文标准名称】:StandardGuideforAssessmentofAntimicrobialActivityUsingaTime-KillProcedure
【原文标准名称】:用Time-Kill法评定抗菌剂活性的标准指南
【标准号】:ASTME2315-2003(2008)
【标准状态】:现行
【国别】:美国
【发布日期】:2003
【实施或试行日期】:
【发布单位】:美国材料与试验协会(US-ASTM)
【起草单位】:E35.15
【标准类型】:(Guide)
【标准水平】:()
【中文主题词】:
【英文主题词】:antimicrobial;invitro;log10reduction;percentreduction;time-kill;Aerobic/anaerobicbiodegradation;Antimicrobialformulations/testing;Inoculumprocessing;Log10reduction;Microbialenvironmen
【摘要】:Thisproceduremaybeusedtoassesstheinvitroreductionofamicrobialpopulationoftestorganismsafterexposuretoatestmaterial.1.1Thisguidecoversexamplesofabasicmethodtomeasurethechangesofapopulationofaerobicmicroorganismswithinaspecifiedsamplingtimewhentestedagainstantimicrobialtestmaterialsinvitro.Severaloptionsfororganismselectionandgrowth,inoculumpreparation,samplingtimesandtemperaturesareprovided.Whenthebasictechniqueisperformedasaspecifictestmethoditiscriticalwhenevaluatingtheresultstoensurethatsuchvariableshavebeenstandardized.Antimicrobialactivityofspecificmaterials,asmeasuredbythistechnique,mayvarysignificantlydependingonvariablesselected.Itisimportanttounderstandthelimitationsofinvitrotests,especiallycomparisonsofresultsfromtestsperformedunderdifferentcircumstances.Asanexample,testresultsofmicroorganismsrequiringgrowthsupplements,orspecialincubationconditions,maynotbedirectlycomparabletomorerobustorganismsundertheconditionsofasingleprocedure.1.2Knowledgeofmicrobiologicaltechniquesisrequiredforthistest.1.3ThevaluesstatedinSIunitsaretoberegardedasstandard.Nootherunitsofmeasurementareincludedinthisstandard.1.4Thisstandardmayinvolvehazardousmaterials,operationsandequipment.Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappropriatesafetyandhealthpracticesanddeterminetheapplicabilityofregulatoryrequirementspriortouse.
【中国标准分类号】:C12
【国际标准分类号】:07_100_99
【页数】:5P.;A4
【正文语种】:英语